Age- and sex-specific mortality rates were calculated on the basis of 719,147 veterans aged 40–99 y enrolled in the Veteran Affairs Million Veteran Program (2011–2019). Hazard ratios and estimated increase in life expectancy were examined among a subgroup of 276,132 veterans with complete data on 8 lifestyle factors at baseline. The 8 lifestyle factors includednever smoking,physical activity,no excessive alcohol consumption,restorative sleep,nutrition,stress management,social connections,and no opioid use disorder.
From What Matters More for Longevity: Genes or Lifestyle? by Dana G. Smith.
One study published last year, which analyzed the lifestyles of more than 276,000 male and female United States veterans, found that adopting eight healthy behaviors could add up to 24 years to people’s lives. They included eating a healthy diet, getting regular physical activity, sleeping well, managing stress, having strong relationships, and not smoking, abusing opioids or drinking to excess.If the veterans adhered to all eight behaviors, the researchers calculated that they could expect to live to about age 87. To most people, that probably sounds pretty good; after all, it’s almost 10 years longer than the average U.S. life expectancy. But to Dr. Milman, who was not involved in the study, the results showed that “even if you do everything right,” you still can’t expect to live to 100.
[snip]If you want to become a centenarian, you’re going to need a little help from your ancestors. Because the older someone gets, the more genetics seem to matter.Overall, scientists think that how long we live is about 25 percent attributable to our genes, and 75 percent attributable to our environment and lifestyle. But as people near 100 and beyond, those percentages start to flip, said Dr. Thomas Perls, a professor of medicine at the Chobanian and Avedisian School of Medicine at Boston University.Indeed, studies have revealed that many people with exceptionally long lives don’t have healthier habits than the average American. And yet, they live longer and have lower rates of age-related diseases, like heart disease, cancer and dementia.
Smith dances around her question of which matters more, lifestyle or genes. What she doesn't quite say but which he words inadvertently indicate, is that the eight lifestyle choices help you increase the odds of living longer regardless of your genes but that your basic life expectancy is substantially influenced by your genes.
Regardless of your lifestyle, with the right genes, you will live longer than average. With the right lifestyle, you will live longer but your lifespan is mostly determined by your genes.
When you look at the eight lifestyles, but of it devolves to the ancient Greek philosophical argument for the Golden Mean, nothing in excess.
By all means, pursue the Golden Mean but you longevity is in your genes.
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